Category:Virtua Tennis (video game series)
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Category:Video games developed in JapanPediatric risk classification systems in cerebrovascular malformations: Pediatric High-Risk Score (PHRS) to measure the risk of aneurysmal subarachnoid hemorrhage in infants.
The Pediatric High-Risk Score (PHRS) was developed to predict aneurysmal subarachnoid hemorrhage (aSAH) in children. We hypothesized that the PHRS might also help to identify children at increased risk for aSAH due to cerebrovascular malformations (CVMs) and therefore might be useful in the treatment decision-making process. We retrospectively analyzed the data of a consecutive cohort of children with CVMs to compare the predictive performance of the PHRS and the modified PHRS (mPHRS) in the prediction of aSAH and mortality. In addition, we studied the performance of the modified PHRS to identify children with CVMs at risk for aSAH and recommend endovascular therapy. The study cohort included 246 children. Of these children, 86 (35.3%) had aSAH. The PHRS demonstrated a specificity of 82% and a sensitivity of 33% (AUC 0.620) for prediction of an aSAH. The mPHRS showed a specificity of 82% and a sensitivity of 60% (AUC 0.821). The aSAH incidence in the lower PHRS and mPHRS risk groups was significantly lower than in the higher PHRS and mPHRS risk groups, respectively (p and patient). Real-time PCR was performed using SYBR Green PCR Master Mix (Applied Biosystems, Foster City, CA, USA) in an be359ba680
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